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Daniela Alberati Selected Research

(4- (3- fluoro- 5- trifluoromethylpyridin- 2- yl)piperazin- 1- yl)(5- methanesulfonyl- 2- (2,2,2- trifluoro- 1- methylethoxy)phenyl)methanone

8/2018Glycine Transporter Type I (GlyT1) Inhibitor, Bitopertin: A Journey from Lab to Patient.
6/2016Preclinical Reproductive and Developmental Toxicity Profile of a Glycine Transporter Type 1 (Glyt1) Inhibitor.
6/2014Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study.
8/2013Physiologically based pharmacokinetic modelling to predict single- and multiple-dose human pharmacokinetics of bitopertin.
2/2012Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia.
6/2010Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.

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Daniela Alberati Research Topics

Disease

9Schizophrenia (Dementia Praecox)
08/2018 - 12/2003
2Mental Disorders (Mental Disorder)
08/2018 - 06/2016
1beta-Thalassemia (Cooley's Anemia)
08/2018
1Anemia
10/2016
1Sideroblastic Anemia
10/2016
1Iron Overload
10/2016

Drug/Important Bio-Agent (IBA)

8Glycine (Aminoacetic Acid)FDA LinkGeneric
08/2018 - 12/2003
6(4- (3- fluoro- 5- trifluoromethylpyridin- 2- yl)piperazin- 1- yl)(5- methanesulfonyl- 2- (2,2,2- trifluoro- 1- methylethoxy)phenyl)methanoneIBA
08/2018 - 06/2010
5N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
04/2016 - 12/2003
2N-Methylaspartate (NMDA)IBA
04/2016 - 02/2012
1Pharmaceutical PreparationsIBA
08/2018
1IronIBA
10/2016
1Heme (Haem)IBA
10/2016
1Hemoglobins (Hemoglobin)IBA
10/2016
1Antipsychotic Agents (Antipsychotics)IBA
06/2014
1Glycine Plasma Membrane Transport ProteinsIBA
12/2003

Therapy/Procedure

2Therapeutics
12/2010 - 12/2003